DNA damage and repair – Naked Genetics 14.03.14

DNA repair (c) Tom Ellenberger

Every second your DNA is under assault – not just from chemicals in our environment or food, but from the hurly-burly of life within our own cells. We’ll be finding out how DNA gets damaged and repaired, and how researchers are exploiting this to find better treatments for cancer. Plus, liver from skin cells, DNA from ancient teeth, and a scary little gene of the month. 

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In this edition of Naked Genetics

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  • DNA damage (c) Brian E. Hingerty, Oak Ridge National Laboratory

    01:18 – What are carcinogens?

    Professor David Phillips and his team are figuring out how our DNA gets damaged, and which chemicals are responsible

  • Broken chromosomes (c) Unknown

    09:47 – How DNA gets damaged

    It’s not just things in our environment that can damage our
    DNA – the damage can come from within too, as Prof Dan
    Durocher explains.

  • Normal liver (c) Harold Ellis

    15:21 – Liver from skin

    A breakthrough from researchers in California could provide a solution to the shortage of donor organs for liver transplants in the future.

  • Models of human teeth as they exist within the alveolar bone (c) DRosenbach

    17:37 – Ancient tooth microbes

    A team led by scientists from Switzerland, Denmark and the UK have unearthed a ‘microbial Pompeii’ on the teeth of 1,000 year old skeletons

  • DNA Helix (c)

    18:41 – DNA repair, and cancer

    Professor Steve Jackson explains how research into DNA damage and repair is leading to new treatments for cancer.

  • An eye (c) jefras a.k.a Joăo Estęvăo A. de Freitas

    24:42 – Can retinitis pigmentosa be cured?

    I have been blind for something over 40 years from a disease called Retinitis pigmentosa. It is caused by a recessive gene. It is said to be incurable.

    Some years ago, it was announced in the news that someone had been cured or partially cured of Retinitis pigmentosa using gen…

  • Gremlins poster (c) US NARA

    28:05 – Gene of the Month – Gremlin

    Sharing a name with the cute but havoc-wreaking creatures in the classic 80s film, Gremlin was first discovered in frog embryos.

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