Gene therapy – Cystic fibrosis, blindness and more – Naked Genetics 14.06.14

Gene therapy – Cystic fibrosis, blindness and more

Retroviral gene therapy vector (c) Jacob Mikkelsen / eLife

Twenty years ago, gene therapy was a great hope for the future of medicine – directly tinkering with faulty genes to cure diseases, but progress has been slow. Now, things seem to be changing. Plus, silencing crickets, evolving brain and brawn, and a flowery gene of the month.

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In this edition of Naked Genetics

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  • field crickets (c) Arpingstone @en.wikipedia

    14:44 – How crickets lost their chirp

    Crickets living on the tropical paradise of Hawaii have lost their chirp, and researchers have figured out why.

  • Mohawk (c) Immanuel Giel

    15:41 – Mice with mohawks

    Mice with mohawk hairstyles could shed light on the human developmental condition autism, according to new research in the journal Nature.

  • Young Male Chimp (c) Frans de Waal, Emory University

    16:46 – Evolving brain and brawn

    Researchers have discovered that differences between humans and chimps evolved rapidly in our brain and brawn.

  • Blind mole rat (c) Gustav Mutzel

    17:59 – Blind mole rat genome

    Researchers have deciphered the genome sequence of the blind mole rat – an unusual underground creature that is resistant to cancer.

  • Scissors (c) Dave Ansell

    19:29 – Dr Jacob Mikkelsen – Chopping genes

    Jacob Giehm Mikkelsen and his team at Aarhus university in Denmark have found a way to use a modified version of HIV to edit DNA in cells.

  • Mowing the grass (c) anitapatterson @ morguefile

    26:04 – How many genes do I share with grass?

    Given that all life on earth is supposed to be Descended from a common source how much of our DNA do we share with some thing like a blade of grass?

  • Snapdragon (c) Rosendahl

    28:27 – Gene of the Month – Delila

    And finally it’s time for our gene of the month, and this time we’re venturing into the garden with a gene called Delila.

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